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Chicken Leukemia Inhibitory Factor (LIF) Recombinant Protein - 5 micrograms

RP1395C-005
$150.00
Data SheetAdd to Cart
Bulk quantities of proteins are available. Please contact us for bulk pricing.

Leukemia inhibitory factor, or LIF, is a member of the IL-6 family. LIF affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. Leukemia inhibitory factor derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to LIF include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. LIF is typically added to stem cell culture medium to reduce spontaneous differentiation.


LIF Homology Across Species
Gallus gallus (chicken) LIF – 100%
Coturnix japonica (Japanese quail) LIF – 97%
Meleagris gallopavo (turkey) LIF – 96%
Colinus virginianus (northern bobwhite) LIF – 95%

Catalog No.:
RP1395C-005
Quantity:
5 ug
Source:
The Chicken LIF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Chicken LIF recombinant protein has a predicted molecular weight of 21.0 kDa.
Protein Sequence:
RALLGTSSAC PTNGLCRANV LEQTRRQVAL LNATAQDLFS LYLKCQGEPF SSESDRLCSP SGIFFPPFHV NRTTERKEVM VAMYKLFAFL NASLGNITRD QEELNPMAKE LLNRLHNTTK TTRGLISNLT CLLCKHYNIF QVDVSYGESS KDKSAFKKKQ QGCQVLRKYV QVIAQAARVL LPHLSPA (187)
Alias:
LIF
Country of Origin:
USA
Applications:
The Chicken LIF endotoxin-free recombinant protein can be used in cell culture, as an LIF ELISA Standard, and as a Western Blot Control.
None at this time

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Kingfisher Biotech, Inc.
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USA

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