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Bovine IL-12 p70 (Yeast-derived Recombinant Protein) - 25 micrograms

RP2168B-025
$300.00
In Stock
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Bulk quantities of Bovine IL-12 p70 protein are available.
Please contact us for pricing.

Bovine IL-12 p70 Specifications

Molecular Weight (calculated) - 57.6kDa

Amino Acid Sequence - MWELEKNVYV VELDWYPDAP GETVVLTCDT PEEDGITWTS DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEALSRSLL LLHKKEDGIW STDILKDQKE PKAKSFLKCE AKDYSGHFTC WWLTAISTDL KFSVKSSRGS SDPRGVTCGA ALLSAEKVSL EHREYNKYTV ECQEGSACPA AEESLLIEVV VEAVHKLKYE NYTSSFFIRD IIKPDPPKNL QLRPLKNSRQ VEVSWEYPDT WSTPHSYFSL TFCVQVQGKN KREKKLFMDQ TSAKVTCHKD ANVRVQARDR YYSSFWSEWA SVSCS (305) **LINKER** RSLPTTTASP GRSCLDYSQN LLRAVSNTLQ KARQTLEFYS CTSEEIDHED ITKDKTSTVE ACLPLELATN ESCLASRETS FITNGHCLAS GKTSFMTTLC LRSIYEDLKM YHVEFQAMNA KLLMDPKRQI FLDQNMLAAI AELMQALNFD SETVPQKPSL KELDFYKTKV KLCILLHAFR IRAVTIDRMM SYLSSS (196)

Gene ID - 281856 (p35 subunit); 281857 (p70 subunit)

Homology Across Species
Bos taurus (cattle) IL-12p70 - 100%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

IL-12 p70 Background

IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-gamma and TNF-alpha from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-gamma.

Alternate Names - IL-12A, CLMF1, NKSF1, p35; IL-12B, CLMF2, NKSF2, p40

Catalog No.:
RP2168B-025
Quantity:
25 ug
Source:
The Bovine IL-12 p70 recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Bovine IL-12 p70 recombinant protein has a predicted molecular weight of 57.6 kDa.
Protein Sequence:

MWELEKNVYV VELDWYPDAP GETVVLTCDT PEEDGITWTS DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEALSRSLL LLHKKEDGIW STDILKDQKE PKAKSFLKCE AKDYSGHFTC WWLTAISTDL KFSVKSSRGS SDPRGVTCGA ALLSAEKVSL EHREYNKYTV ECQEGSACPA AEESLLIEVV VEAVHKLKYE NYTSSFFIRD IIKPDPPKNL QLRPLKNSRQ VEVSWEYPDT WSTPHSYFSL TFCVQVQGKN KREKKLFMDQ TSAKVTCHKD ANVRVQARDR YYSSFWSEWA SVSCS (305) **LINKER** RSLPTTTASP GRSCLDYSQN LLRAVSNTLQ KARQTLEFYS CTSEEIDHED ITKDKTSTVE ACLPLELATN ESCLASRETS FITNGHCLAS GKTSFMTTLC LRSIYEDLKM YHVEFQAMNA KLLMDPKRQI FLDQNMLAAI AELMQALNFD SETVPQKPSL KELDFYKTKV KLCILLHAFR IRAVTIDRMM SYLSSS (196)

Country of Origin:
USA
Applications:
The Bovine IL-12 p70 endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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