Bulk pricing on proteins is available. Call us at 651-646-0089 or send us an email.
Vascular endothelial growth factor (VEGF) proteins stimulate vasculogenesis and angiogenesis. They are part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. The normal function of VEGF proteins is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. The VEGF family has six members, including VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and Placental Growth Factor (PGF). Activity of VEGF-A, as its name implies, has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g., stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells). In vitro, VEGF-A has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF).
VEGF-A Homology Across Species
Bos taurus (cattle) VEGF-A – 100%
Bison bison (bison) VEGF-A – 100%
Bos mutus (wild yak) VEGF-A – 100%
Bubalus bubalis (water buffalo) VEGF-A – 100%
Ovis aries (sheep)VEGF-A – 99%
Capra hircus (goat) VEGF-A – 99%
Orcinus orca (killer whale) VEGF-A – 96%
Physeter catodon (sperm whale) VEGF-A – 96%
Lipotes vexillifer (Yangtze River dolphin) VEGF-A – 96%
Orcinus orca (killer whale) VEGF-A – 96%
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) VEGF-A – 96%
Chrysochloris asiatica (Cape golden mole) VEGF-A – 96%
Condylura cristata (star-nosed mole) VEGF-A – 95%
Camelus ferus (Wild Bactrian camel) VEGF-A – 95%
Neovison vison (American mink) VEGF-A – 95%
Ochotona curzoniae (black-lipped pika) VEGF-A – 95%
Callithrix jacchus (white-tufted-ear marmoset) VEGF-A – 95%
Cebus capucinus imitator(white-faced capuchin) VEGF-A – 95%
Ursus maritimus (polar bear) VEGF-A – 95%
Please note that Cookies and JavaScript are required for you to view this website.
Check if you have Cookies and JavaScript enabled in your browser