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CartHuman Oncostatin M (OSM) Do-It-Yourself ELISA, ≤20 Plates
Human Oncostatin M (OSM) ELISA Data
Human Oncostatin M (OSM) ELISA Kit Components
| Component | Usage | Quantity | Catalog # |
| Anti-Human Oncostatin M (OSM) Polyclonal Antibody | Capture Antibody | 100 µg X 2 | KP1493H-100 |
| Biotinylated Anti-Human Oncostatin M (OSM) Polyclonal Antibody | Detection Antibody | 50 µg | KPB1494H-050 |
| Human Oncostatin M (OSM) Recombinant Protein | Standard | 5 µg | RP1283H-005 |
Human Oncostatin M (OSM) ELISA Specifications
The Human Oncostatin M (OSM)-A Do-It-Yourself ELISA contains capture antibody, standard, and detection antibody for development of a Human Oncostatin M (OSM) ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
Oncostatin M (OSM) Background
OSM (Oncostatin M) is a secreted cytokine involved in homeostasis and most chronic illnesses. OSM, a member of the IL-6 (gp130) family of proteins, inhibits the proliferation of a number of tumor cell lines and plays a significant role in hematopoiesis, mesenchymal stem cell differentiation, liver regeneration, heart remodeling, nociception, inflammation and metabolism. Of all IL-6-type cytokines studied so far, OSM displays the broadest signaling profile. LIF and OSM proteins activate the JAK/STAT pathway, the MAPK protein kinases ERK1 and ERK2, the stress-activated protein kinases p38 and c-Jun N-terminal kinase (JNK), the phosphatidylinositol-3-kinase (PI3K) AKT pathway and protein kinase C delta (PRKCD). In addition, OSM exhibits many other effects by regulating the production of other cytokines including IL-6, G-CSF and GM-CSF in endothelial cells. OSM may be a tumor promoter that will provide a potential target for antiangiogenic therapy.
Alternate Names - OSM, Osm, OncoM, oncostatin M
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Kingfisher Biotech, Inc.
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