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CartBovine CTLA-4 Do-It-Yourself ELISA, ≤20 Plates
Bovine CTLA-4 ELISA Data
Bovine CTLA-4 ELISA Kit Components
| Component | Usage | Quantity | Catalog # |
| Anti-Bovine CTLA-4 Polyclonal Antibody | Capture Antibody | 100 µg X 2 | KP1972B-100 |
| Biotinylated Anti-Bovine CTLA-4 Polyclonal Antibody | Detection Antibody | 50 µg | KPB1973B-050 |
| Bovine CTLA-4 Recombinant Protein | Standard | 5 µg | RP1411B-005 |
Bovine CTLA-4 ELISA Specifications
The Bovine CTLA-4 Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Bovine CTLA-4 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
The Bovine CTLA-4 Do-It-Yourself ELISA can also be used to measure Bison, Carabao, Wild Yak, Water Buffalo, and Zebu CTLA-4.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
CTLA-4 Background
CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. It is a member of the Ig gene superfamily and along with its homologue, CD28, is a B7 binding protein. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Alternatively spliced mRNA generates a soluble form, called sCTLA-4. Whereas low levels of sCTLA-4 are detected in normal human serum, increased/high serum levels are observed in several autoimmune diseases.
Alternate Names - CTLA4, ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, cytotoxic T-lymphocyte associated protein 4
Ordering Information & Terms and Conditions
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.
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Returns
Please call customer service before returning any products for refund, credit or replacement. NO returns will be accepted without prior written authorization. Returns are subject to a restocking fee of 20%.