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CartCanine IL-36RA Do-It-Yourself ELISA, ≤10 Plates
Canine IL-36RA ELISA Data
Canine IL-36RA ELISA Kit Components
| Component | Usage | Quantity | Catalog # |
| Anti-Canine IL-36RA Polyclonal Antibody | Capture Antibody | 100 µg | KP2178D-100 |
| Biotinylated Anti-Canine IL-36RA Polyclonal Antibody | Detection Antibody | 50 µg | KPB2179D-050 |
| Canine IL-36RA Recombinant Protein | Standard | 5 µg | RP1997D-005 |
Canine IL-36RA ELISA Specifications
The Canine IL-36RA Do-It-Yourself ELISA contains capture antibody, standard, and detection antibody for development of a Canine IL-36RA ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
The Canine IL-36RA Do-It-Yourself ELISA can also be used to measure Dingo and Fox IL-36RA.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
IL-36RA Background
The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
Alternate Names - IL36RN, FIL1, FIL1(DELTA), FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, IL-36Ra, PSORS14, interleukin 36 receptor antagonist
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Kingfisher Biotech, Inc.
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