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CartCanine VEGF-A (Yeast-derived Recombinant Protein) - 25 micrograms
Vascular endothelial growth factor (VEGF) proteins stimulate vasculogenesis and angiogenesis. They are part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. The normal function of VEGF proteins is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. The VEGF family has six members, including VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and Placental Growth Factor (PGF). Activity of VEGF-A, as its name implies, has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g., stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells). In vitro, VEGF-A has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF).
Alternate Names - VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A
VEGF-A Homology Across Species
Canis lupus familiaris (dog) VEGF-A – 100%
Canis lupus dingo (dingo) VEGF-A – 100%
Nyctereutes procyonoides (raccoon dog) VEGF-A – 100%
Vulpes lagopus (Arctic fox) VEGF-A – 100%
Vulpes vulpes (red fox) VEGF-A – 100%
Leptonychotes weddellii (Weddell seal) VEGF-A – 99%
Mustela putorius furo (domestic ferret) VEGF-A – 99%
Odobenus rosmarus divergens (Pacific walrus) VEGF-A – 99%
Acinonyx jubatus (cheetah) VEGF-A – 97%
Camelus bactrianus (Bactrian camel) VEGF-A – 97%
Camelus ferus (Wild Bactrian camel) VEGF-A – 97%
Felis catus (domestic cat) VEGF-A – 97%
Orcinus orca (killer whale) VEGF-A – 97%
Panthera pardus (leopard) VEGF-A – 97%
Physeter catodon (sperm whale) VEGF-A – 97%
More - https://blast.ncbi.nlm.nih.gov/
Interleukin-1β, tumour necrosis factor-α and lipopolysaccharide induce C-type natriuretic peptide from canine aortic endothelial cells.
Osterbur K, Yu DH, Declue AE.
Res Vet Sci. 2012 Nov 8. doi:pii: S0034-5288(12)00305-0. 10.1016/j.rvsc.2012.10.002.
Applications: Stimulation of canine aortic endothelial cells
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Kingfisher Biotech, Inc.
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