Bulk quantities of Human APRIL protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 16.4kDa
Amino Acid Sequence - AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL (146)
Gene ID - 8741
Homology Across Species
Homo sapiens (human) APRIL – 100%
Pan paniscus (pygmy chimpanzee) APRIL – 100%
Pan troglodytes (chimpanzee) APRIL – 100%
Cercocebus atys (sooty mangabey) APRIL – 99%
Chlorocebus sabaeus (green monkey) APRIL – 99%
Gorilla gorilla gorilla (western lowland gorilla) APRIL – 99%
Macaca fascicularis (crab-eating macaque) APRIL – 99%
Macaca mulatta (Rhesus monkey) APRIL – 99%
Mandrillus leucophaeus (drill) APRIL – 99%
Nomascus leucogenys (northern white-cheeked gibbon) APRIL – 99%
Pongo abelii (Sumatran orangutan) APRIL – 99%
Rhinopithecus roxellana (golden snub-nosed monkey) APRIL – 99%
Papio anubis (olive baboon) APRIL – 98%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Tumor necrosis factor ligand superfamily member 13 (TNFSF13) also known as a proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18). APRIL/TNFSF13 is expressed by macrophages and dendritic cells. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development.
Alternate Names - TNFSF13, APRIL, CD256, TALL-2, TALL2, TRDL-1, ZTNF2, UNQ383/PRO715, TNLG7B, tumor necrosis factor superfamily member 13, TNF superfamily member 13
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