Bulk quantities of Mouse CXCL12 protein are available.
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Molecular Weight (calculated) - 11.6kDa
Amino Acid Sequence - GKPVSLSYRC PCRFFESHIA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKG RREEKVGKKE KIGKKKRQKK RKAAQKRKN (99)
Gene ID - 20315
Homology Across Species
Mus musculus (house mouse) CXCL12 – 100%
Mus pahari (shrew mouse) CXCL12 – 100%
Mus caroli (Ryukyu mouse) CXCL12 – 100%
Sturnira hondurensisCXCL12 – 99%
Artibeus jamaicensis (Jamaican fruit-eating bat) CXCL12 – 99%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
CXCL12 (formerly stromal cell-derived factor 1) was originally described as a vital chemoattractant for B cells and monocytes. CXCL12 is unlike other chemokines in that it binds to one single chemokine receptor, CXCR4, which itself is recognized by no other chemokines. CXCL12 binds to its receptor CXCR4 to mediate cell-type specific physiological processes including cellular migration, survival, and apoptosis. CXCL12 is produced physiologically in various tissues and its receptor CXCR4 is also expressed on various haematopoietic and non-haematopoietic cells. CXCL12 and CXCR4 are essential for life as mice deficient in either gene are unable to survive much past birth. CXCL12 and CXCR4 play a role in many different diseases, including cancer, HIV, and rheumatoid arthritis.
Alternate Names - CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12
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