Bulk quantities of Caprine/Ovine IL-8 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 9.1kDa
Amino Acid Sequence - AVLSRMSTEL RCQCIKTHST PFHPKFIKEL RVIESGPHCE NSEIIVKLTN GKEVCLDPKE KWVQKVVQAF LKRAEKQDP (79)
Gene ID - 443418 (ovine) 102178438 (caprine)
Homology Across Species
Ovis aries (sheep) IL-8 – 100%
Ovis canadensis (bighorn sheep) IL-8 – 100%
Capra hircus (goat) IL-8 – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2.
Alternate Names - CXCL8, chemokine (C-X-C motif) ligand 8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, IL8, C-X-C motif chemokine ligand 8, Interleukin-8
Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma.
Bouquet M, Passmore MR, See Hoe LE, Tung JP, Simonova G, Boon AC, Fraser JF.
J Immunol Methods. 2020 Aug 20:112835. doi: 10.1016/j.jim.2020.112835. Online ahead of print.
Applications: Standards for the measurement of ovine IL-1 beta, IL-6, IL-8, and IL-10 in plasma by ELISA
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