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Canine IL-13 (Yeast-derived Recombinant Protein) - 100 micrograms

RP0737D-100
$900.00
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Bulk quantities of Canine IL-13 protein are available.
Please contact us for pricing.

Canine IL-13 Specifications

Molecular Weight (calculated) - 12.3kDa

Amino Acid Sequence - SPSPVTPSPT LKELIEELVN ITQNQASLCN GSMVWSVNLT AGMYCAALES LINVSDCSAI QRTQRMLKAL CSQKPAAGIS SERSRDTKIE VIQLVKNLLT YVRGVYRHGN FR (112)

Gene ID - 442990

Homology Across Species
Canis lupus familiaris (dog) IL-13 – 100%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

IL-13 Background

Interleukin 13 (IL-13) is secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. Thus, although IL-13 can induce immunoglobulin E (IgE) secretion from activated human B cells, deletion of IL-13 from mice does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. In comparison, deletion of IL-4 abrogates these responses. Thus, rather than a lymphoid cytokine, IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Alternate Names - IL13, IL-13, P600, interleukin 13

Canine IL-13 (Yeast-derived Recombinant Protein) - 100 micrograms
Catalog No.:
RP0737D-100
Quantity:
100 ug
Source:
Canine IL-13 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
Canine IL-13 has a predicted molecular weight of 12.3 kDa.
Protein Sequence:
SPSPVTPSPT LKELIEELVN ITQNQASLCN GSMVWSVNLT AGMYCAALES LINVSDCSAI QRTQRMLKAL CSQKPAAGIS SERSRDTKIE VIQLVKNLLT YVRGVYRHGN FR (112)
Country of Origin:
USA
Applications:
The Canine IL-13 endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.