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Caprine IL-1 beta (Yeast-derived Recombinant Protein) - 25 micrograms

RP1053G-025
$300.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.

Alternate Names - IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta, IL1beta

Homology Across Species
Capra hircus (goat) IL-1ß - 100%
Pseudois nayaur (bharal) IL-1ß - 99%
Ovis aries (sheep) IL-1ß - 99%
Oryx dammah (scimitar-horned oryx) IL-1ß - 99%
More - https://blast.ncbi.nlm.nih.gov/

Caprine IL-1 beta (Yeast-derived Recombinant Protein) - 25 micrograms
Catalog No.:
RP1053G-025
Quantity:
25 ug
Source:
The Caprine IL-1 beta recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Caprine IL-1 beta recombinant protein has a predicted molecular weight of 17.7 kDa.
Protein Sequence:
AAVQSVKCKL QDREQKSLVL DSPCVLKALH LLSQEMSREV VFCMSFVQGE ERDNKIPVAL GIRDKNLYLS CVKKGDTPTL QLEEVDPKVY PKRNMEKRFV FYKTEIKNTV EFESVLYPNW YISTSQIEEK PVFLGHFRGG QDITDFRMET LSP (153)
Alias:
IL-1F2
Country of Origin:
USA
Applications:
The Caprine IL-1 beta endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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