Bulk quantities of Canine Fas Ligand protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 17.3kDa
Amino Acid Sequence - QIGQPNPPSE KRELRKVAHL TGKPNSRSIP LEWEDTYGIA LVSGVKYKKG GLVINDTGLY FVYSKVYFRG QSCNNKPLNH KVYMRNSKYP QDLMLMEGKI MNYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVSF EESKTFFGLY KL (152)
Gene ID - 442968
Homology Across Species
Canis lupus familiaris (dog) Fas Ligand – 100%
Canis lupus dingo (dingo) Fas Ligand – 100%
Vulpes vulpes (red fox) Fas Ligand – 100%
Neomonachus schauinslandi (Hawaiian monk seal) Fas Ligand – 98%
Ursus maritimus (polar bear) Fas Ligand – 98%
Ursus arctos horribilis (grizzly bear) Fas Ligand – 98%
Ailuropoda melanoleuca (giant panda) Fas Ligand – 98%
Leptonychotes weddellii (Weddell seal) Fas Ligand – 98%
Odobenus rosmarus divergens (Pacific walrus) Fas Ligand – 97%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
The Fas ligand (FasL), also known as CD95L and TNFSF6, is a homotrimeric type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily. FasL plays diverse roles in the immune system, including induction of apoptotic cell death in target cells. FasL-Fas-mediated apoptosis plays fundamental roles in several immune functions. The pathway is involved in functions including regulation of T cell homeostasis and maintenance of immune privilege, apart from its well-established role in T cell-mediated cytotoxicity. Cytotoxicity via the Fas pathway is critical for prevention of pathogenic infections as well as control of tumor cell growth.
Alternate Names - FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, Fas ligand
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