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CartDolphin IL-13 (Yeast-derived Recombinant Protein) - 25 microgrmas
Bulk quantities of Dolphin IL-13 protein are available.
Please contact us for pricing.
Dolphin IL-13 Specifications
Molecular Weight (calculated) - 12.4kDa
Amino Acid Sequence - GPVPPSTALK ELIEELVNIT QNQKAPLCNG SMVWSVNLTA NMYCSALEAL INVSNCSAIQ RTQRMLSALC LHKPSAGQVS SEHIRDTKIE VAHFLKDLLK HSRIIFHYGK FS (112)
Gene ID - 101338603
Homology Across Species
Tursiops truncatus (common bottlenose dolphin) IL-13 – 100%
Orcinus orca (killer whale) IL-13 – 100%
Globicephala melas (long-finned pilot whale) IL-13 – 100%
Phocoena sinus (vaquita) IL-13 – 100%
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) IL-13 – 100%
Lipotes vexillifer (Yangtze River dolphin) IL-13 – 99%
Lagenorhynchus obliquidens (Pacific white-sided dolphin) IL-13 – 98%
Delphinapterus leucas (beluga whale) IL-13 – 98%
Physeter catodon (sperm whale) IL-13 – 96%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
IL-13 Background
Interleukin 13 (IL-13) is secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. Thus, although IL-13 can induce immunoglobulin E (IgE) secretion from activated human B cells, deletion of IL-13 from mice does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. In comparison, deletion of IL-4 abrogates these responses. Thus, rather than a lymphoid cytokine, IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Alternate Names - IL13, IL-13, P600, interleukin 13
Ordering Information & Terms and Conditions
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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