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CartDolphin CXCL10 (IP-10) (Yeast-derived Recombinant Protein) - 5 micrograms
Bulk quantities of proteins are available. Please contact us for bulk pricing.
C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Alternate Names - CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10
Homology Across Species
Tursiops truncatus (common bottlenose dolphin) CXCL10 – 100%
Orcinus orca (killer whale) CXCL10 – 100%
Delphinapterus leucas (beluga whale) CXCL10 – 100%
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) CXCL10 – 100%
Lagenorhynchus obliquidens (Pacific white-sided dolphin) CXCL10 – 100%
Globicephala melas (long-finned pilot whale) CXCL10 – 100%
Phocoena sinus (vaquita) CXCL10 – 100%
Monodon monoceros (narwhal) CXCL10 – 99%
Lipotes vexillifer (Yangtze River dolphin) CXCL10 – 98%
​More - https://blast.ncbi.nlm.nih.gov/
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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