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CartChicken SCF (Stem Cell Factor) (Yeast-derived Recombinant Protein) - 100 micrograms
Bulk quantities of Chicken SCF protein are available.
Please contact us for pricing.
Chicken SCF Specifications
Molecular Weight (calculated) - 22.5kDa
Amino Acid Sequence - QSSCGNPVTD DVNDIAKLVG NLPNDYLITL KYVPKMDSLP NHCWLHLMVP EFSRSLHNLL QKFSDISDMS DVLSNYSIIN NLTRIINDLM ACLAFDKNKD FIKENGHLYE EDRFIPENFF RLFNSTIEVY KEFADSLDKN DCIMPSTVET PENDSRVAVT KTISFPPVAA SSLRNDSIGS NTSSNSNKEA LGFISSSSLQ (200)
Gene ID - 396028
Homology Across Species
Gallus gallus (chicken) SCF – 100%
Centrocercus urophasianus (Greater sage-grouse) SCF – 99%
Tympanuchus pallidicinctus (lesser prairie-chicken) SCF – 99%
Phasianus colchicus (Ring-necked pheasant) SCF – 99%
Coturnix japonica (Japanese quail) SCF – 99%
Coturnix coturnix (Common quail) SCF – 99%
Meleagris gallopavo (turkey) SCF – 98%
Numida meleagris (helmeted guineafowl) SCF – 98%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
SCF Background
SCF, often known as Kit Ligand, KITL or KITLG, is involved in pathways that control the regulation of cell survival, migration and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, and melanogenesis. SCF binding to the receptor-type protein-tyrosine kinase KIT, induces a cell signaling pathway that activates several other cell signaling pathways, including PIK3R1/AKT1, GRB2, RAS, RAF1, MAPK1/ERK2, MAPK3/ERK1, and STAT signaling events. The effects of SCF on these secondary pathways further allow it to play a role in many or the major cellular processes. The SCF, of most vertebrates, has a soluble form as well as the membrane bound type I receptor form. Mutations in the SCF pathway may result in a broad range of abnormalities including anemia, and sterility. SCF and KIT interaction has been shown to promote the growth of cancer cells and organoids in culture, and xenograft tumors in mice. SCF is being utilized in many animal model systems, from metastasis research in breast tumor-bearing arthritic mice to the genetic linkage to de-pigmentation in pigs. Interestingly, a second SCF pathway was retained in zebrafish, after a whole genome duplication, and is now undergoing divergent evolution.
Alternate Names - KITLG, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, DCUA, KIT ligand, DFNA69, SLF
QSSCGNPVTD DVNDIAKLVG NLPNDYLITL KYVPKMDSLP NHCWLHLMVP EFSRSLHNLL QKFSDISDMS DVLSNYSIIN NLTRIINDLM ACLAFDKNKD FIKENGHLYE EDRFIPENFF RLFNSTIEVY KEFADSLDKN DCIMPSTVET PENDSRVAVT KTISFPPVAA SSLRNDSIGS NTSSNSNKEA LGFISSSSLQ (200)
Ordering Information & Terms and Conditions
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Via Phone
Please call us at 651-646-0089 between the hours of 8:30 a.m. and 5:30 p.m. CST Mon - Fri.
Via Fax
Orders can be faxed to us 24 hours a day at 651-646-0095.
Via E-mail
Please e-mail orders to orders@KingfisherBiotech.com.
Via Mail
Please mail your order to:
Sales Order Entry
Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
Product Warranty
Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.
Payment Terms
All prices are subject to change without notice. Payment terms are net thirty (30) days from receipt of invoice. A 1.5% service charge per month is added for accounts past due over 30 days. Prices quoted are U.S. Dollars. The purchaser assumes responsibility for any applicable tax. You will only be charged for products shipped. Products placed on back order will be charged when shipped. If you place an order and fail to fulfill the terms of payment, Kingfisher Biotech, Inc. may without prejudice to any other lawful remedy defer further shipments and/or cancel any order. You shall be liable to Kingfisher Biotech, Inc. for all costs and fees, including attorneys' fees, which Kingfisher Biotech, Inc. may reasonably incur in any actions to collect on your overdue account. Kingfisher Biotech, Inc. does not agree to, and is not bound by, any other terms or conditions such as terms in a purchase order that have not been expressly agreed to in writing signed by a duly authorized officer of Kingfisher Biotech, Inc.
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Returns
Please call customer service before returning any products for refund, credit or replacement. NO returns will be accepted without prior written authorization. Returns are subject to a restocking fee of 20%.