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Chicken SCF (Stem Cell Factor) (Yeast-derived Recombinant Protein) - 100 micrograms

RP1555C-100
$900.00
In Stock
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Bulk quantities of Chicken SCF protein are available.
Please contact us for pricing.

Chicken SCF Specifications

Molecular Weight (calculated) - 22.5kDa

Amino Acid Sequence - QSSCGNPVTD DVNDIAKLVG NLPNDYLITL KYVPKMDSLP NHCWLHLMVP EFSRSLHNLL QKFSDISDMS DVLSNYSIIN NLTRIINDLM ACLAFDKNKD FIKENGHLYE EDRFIPENFF RLFNSTIEVY KEFADSLDKN DCIMPSTVET PENDSRVAVT KTISFPPVAA SSLRNDSIGS NTSSNSNKEA LGFISSSSLQ (200)

Gene ID - 396028

Homology Across Species
Gallus gallus (chicken) SCF – 100%
Centrocercus urophasianus (Greater sage-grouse) SCF – 99%
Tympanuchus pallidicinctus (lesser prairie-chicken) SCF – 99%
Phasianus colchicus (Ring-necked pheasant) SCF – 99%
Coturnix japonica (Japanese quail) SCF – 99%
Coturnix coturnix (Common quail) SCF – 99%
Meleagris gallopavo (turkey) SCF – 98%
Numida meleagris (helmeted guineafowl) SCF – 98%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

SCF Background

SCF, often known as Kit Ligand, KITL or KITLG, is involved in pathways that control the regulation of cell survival, migration and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, and melanogenesis. SCF binding to the receptor-type protein-tyrosine kinase KIT, induces a cell signaling pathway that activates several other cell signaling pathways, including PIK3R1/AKT1, GRB2, RAS, RAF1, MAPK1/ERK2, MAPK3/ERK1, and STAT signaling events. The effects of SCF on these secondary pathways further allow it to play a role in many or the major cellular processes. The SCF, of most vertebrates, has a soluble form as well as the membrane bound type I receptor form. Mutations in the SCF pathway may result in a broad range of abnormalities including anemia, and sterility. SCF and KIT interaction has been shown to promote the growth of cancer cells and organoids in culture, and xenograft tumors in mice. SCF is being utilized in many animal model systems, from metastasis research in breast tumor-bearing arthritic mice to the genetic linkage to de-pigmentation in pigs. Interestingly, a second SCF pathway was retained in zebrafish, after a whole genome duplication, and is now undergoing divergent evolution.

Alternate Names - KITLG, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, DCUA, KIT ligand, DFNA69, SLF

Catalog No.:
RP1555C-100
Quantity:
100 ug
Source:
The Chicken SCF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Chicken SCF recombinant protein has a predicted molecular weight of 22.5 kDa.
Protein Sequence:

QSSCGNPVTD DVNDIAKLVG NLPNDYLITL KYVPKMDSLP NHCWLHLMVP EFSRSLHNLL QKFSDISDMS DVLSNYSIIN NLTRIINDLM ACLAFDKNKD FIKENGHLYE EDRFIPENFF RLFNSTIEVY KEFADSLDKN DCIMPSTVET PENDSRVAVT KTISFPPVAA SSLRNDSIGS NTSSNSNKEA LGFISSSSLQ (200)

Alias:
Kit Ligand, Stem Cell Factor
Country of Origin:
USA
Applications:
The Chicken SCF endotoxin-free recombinant protein can be used in cell culture, as an SCF ELISA Standard, and as a Western Blot Control.
None at this time

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Kingfisher Biotech, Inc.
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Suite 123
Saint Paul, MN 55114
USA

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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.

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