Bulk quantities of Ferret/Mink CXCL10 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 8.5kDa
Amino Acid Sequence - VPLSRTTRCT CIKISDGSIN PRSLEKLEVI PASQSCPRVE IIATLKKNGE KRCLNPASKK IKILLKAISK ERSKTSP (77)
Gene ID - 101692969 (Ferret)
Homology Across Species
Mustela putorius furo (domestic ferret) CXCL10 – 100%
Neogale vison (American mink) CXCL10 – 100%
Mustela erminea (ermine) CXCL10 – 100%
Enhydra lutris kenyoni (sea otter) CXCL10 – 97%
Lontra canadensis (Northern American river otter) CXCL10 – 97%
Lutra lutra (Eurasian river otter) CXCL10 – 97%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Alternate Names - CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10
VPLSRTTRCT CIKISDGSIN PRSLEKLEVI PASQSCPRVE IIATLKKNGE KRCLNPASKK IKILLKAISK ERSKTSP (77)
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