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CartFerret/Mink CXCL10 (IP-10) (Yeast-derived Recombinant Protein) - 500 ug (5 x 100 ug vials)
Bulk quantities of Ferret/Mink CXCL10 protein are available.
Please contact us for pricing.
Ferret/Mink CXCL10 Specifications
Molecular Weight (calculated) - 8.5kDa
Amino Acid Sequence - VPLSRTTRCT CIKISDGSIN PRSLEKLEVI PASQSCPRVE IIATLKKNGE KRCLNPASKK IKILLKAISK ERSKTSP (77)
Gene ID - 101692969 (Ferret)
Homology Across Species
Mustela putorius furo (domestic ferret) CXCL10 – 100%
Neogale vison (American mink) CXCL10 – 100%
Mustela erminea (ermine) CXCL10 – 100%
Enhydra lutris kenyoni (sea otter) CXCL10 – 97%
Lontra canadensis (Northern American river otter) CXCL10 – 97%
Lutra lutra (Eurasian river otter) CXCL10 – 97%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
CXCL10 Background
C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Alternate Names - CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10
VPLSRTTRCT CIKISDGSIN PRSLEKLEVI PASQSCPRVE IIATLKKNGE KRCLNPASKK IKILLKAISK ERSKTSP (77)
Ordering Information & Terms and Conditions
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.
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Please call customer service before returning any products for refund, credit or replacement. NO returns will be accepted without prior written authorization. Returns are subject to a restocking fee of 20%.