Bulk quantities of Dolphin TIM-3 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 18.6kDa
Amino Acid Sequence - VYVSEVGQDA DLPCAYSPPT PEDLVPVCWG KGPCPLFQCH SLVLSTDGRN LSYWTSSRYL LKRNFRKGDV TLTIKNVTLE DSGTYCCRIQ FPGLMNDQKS NLELVIKPAK VTPAGTPWRD ITAAFPRMLT TEGPGSETQT LETLHDKNQT EISTLANELQ DMGATTRI (168)
Gene ID - 101331594
Homology Across Species
Tursiops truncatus (common bottlenose dolphin) TIM-3 – 100%
Sousa chinensis (Indo-pacific humpbacked dolphin) TIM-3 – 100%
Lagenorhynchus obliquidens (Pacific white-sided dolphin) TIM-3 – 98%
Orcinus orca (killer whale) TIM-3 – 98%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
TIM-3 is a transmembrane protein of T lymphocytes (CD4+ and CD8+ T cells), myeloid cells (monocytes, macrophages, DC, mast cells, NK cells) or various cells in different tumor types. The receptor is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8+ T-cell exhaustion in terms of proliferation and secretion of cytokines such as TNF-alpha, IFN-gamma and IL-2.
Alternate Names - HAVCR2, HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3, CD366, hepatitis A virus cellular receptor 2, SPTCL
VYVSEVGQDA DLPCAYSPPT PEDLVPVCWG KGPCPLFQCH SLVLSTDGRN LSYWTSSRYL LKRNFRKGDV TLTIKNVTLE DSGTYCCRIQ FPGLMNDQKS NLELVIKPAK VTPAGTPWRD ITAAFPRMLT TEGPGSETQT LETLHDKNQT EISTLANELQ DMGATTRI (168)
Please note that Cookies and JavaScript are required for you to view this website.
Check if you have Cookies and JavaScript enabled in your browser