Bulk quantities of Multi-species CXCL12 (Bat, Dolphin, Feline, Guinea Pig, Human, Mink, Monkey) protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 7.6kDa
Amino Acid Sequence - VSLSYRCPCR FFESHVARAN VKHLKILNTP NCALQIVARL KNNNRQVCID PKLKWIQEYL EKALN (65)
Gene ID - 6387 (human)
Homology Across Species
Homo sapiens (human) CXCL12 – 100%
Tursiops truncatus (common bottlenose dolphin) CXCL12 – 100%
Cavia porcellus (domestic guinea pig) CXCL12 – 100%
Felis catus (domestic cat) CXCL12 – 100% CXCL12 – 100%
Macaca fascicularis (crab-eating macaque) CXCL12 – 100%
Rousettus aegyptiacus (Egyptian rousette) CXCL12 – 100%
Desmodus rotundus (common vampire bat) CXCL12 – 100%
Artibeus jamaicensis (Jamaican fruit-eating bat) CXCL12 – 100%
Sturnira hondurensis CXCL12 – 100%
Neogale vison (American mink) CXCL12 – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
CXCL12 (formerly stromal cell-derived factor 1) was originally described as a vital chemoattractant for B cells and monocytes. CXCL12 is unlike other chemokines in that it binds to one single chemokine receptor, CXCR4, which itself is recognized by no other chemokines. CXCL12 binds to its receptor CXCR4 to mediate cell-type specific physiological processes including cellular migration, survival, and apoptosis. CXCL12 is produced physiologically in various tissues and its receptor CXCR4 is also expressed on various haematopoietic and non-haematopoietic cells. CXCL12 and CXCR4 are essential for life as mice deficient in either gene are unable to survive much past birth. CXCL12 and CXCR4 play a role in many different diseases, including cancer, HIV, and rheumatoid arthritis.
Alternate Names - CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12
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