Bulk quantities of Feline IL-12/23 p40 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 35.0kDa
Amino Acid Sequence - IWELEKNVYV VELDWHPDAP GEMVVLTCNT PEEDDITWTS DQSSEVLGSG KTLTIQVKEF ADAGQYTCHK GGEVLSHSFL LIHKKEDGIW STDILREQKE SKNKIFLKCE AKNYSGRFTC WWLTAISTDL KFTVKSSRGS SDPQEVTCGA ATLSAEKVRV DNRDYKKYTV ECQEGSACPA AEESLPIEVV VDAIHKLKYE NYTSSFFIRD IIKPDPPKNL QLKPLKNSRH VEVSWEYPDT WSTPHSYFSL TFGVQVQGKN NREKKDRLSV DKTSAKVVCH KDAKIRVQAR DRYYSSSWSN WASVSCS (307)
Gene ID - 768273
Homology Across Species
Felis catus (domestic cat) – IL-12 p40 – 100%
Leopardus geoffroyi (Geoffroy's cat) IL-12 p40 – 99%
Lynx canadensis (Canada lynx) IL-12 p40 – 99%
Puma yagouaroundi (jaguarundi) IL-12 p40 – 99%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells.[2] It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-gamma and TNF-alpha from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-gamma
Alternate Names - IL12B, CLMF, CLMF2, IL-12B, IMD28, NKSF, NKSF2, IMD29, Interleukin 12 subunit beta, interleukin 12B
IWELEKNVYV VELDWHPDAP GEMVVLTCNT PEEDDITWTS DQSSEVLGSG KTLTIQVKEF ADAGQYTCHK GGEVLSHSFL LIHKKEDGIW STDILREQKE SKNKIFLKCE AKNYSGRFTC WWLTAISTDL KFTVKSSRGS SDPQEVTCGA ATLSAEKVRV DNRDYKKYTV ECQEGSACPA AEESLPIEVV VDAIHKLKYE NYTSSFFIRD IIKPDPPKNL QLKPLKNSRH VEVSWEYPDT WSTPHSYFSL TFGVQVQGKN NREKKDRLSV DKTSAKVVCH KDAKIRVQAR DRYYSSSWSN WASVSCS (307)
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