Bulk quantities of Feline IL-6 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 20.6kDa
Amino Acid Sequence - TPGPLGGDAT SNRLPLTSAD KMEELIKYIL GKISALKKEM CDNYNKCEDS KEALAENNLN LPKLAEKDGC FQSGFNQETC LTRITTGLQE FQIYLKFLQD KYEGDKENAK SVYTSTNVLL QMLKRKGKNQ DEVTIPVPTV EVGLQAKLQS QEEWLRHTTI HLTLRRLEDF LQFSLRAVRI M (181)
Gene ID - 493687
Homology Across Species
Felis catus (domestic cat) IL-6 -100%
Lynx canadensis (Canada lynx) IL-6 -100%
Puma concolor (puma) IL-6 -100%
Puma yagouaroundi (jaguarundi) IL-6 -100%
Acinonyx jubatus (cheetah) IL-6 -100%
This sequence is highly homologous across various species of large cats, including, lion, leopard, lynx, cheetah, puma, and jaguarundi.
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is also produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. Osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. The role of IL-6 as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.
Alternate Names - IL6, BSF2, HGF, HSF, IFNB2, IL-6, BSF-2, CDF, IFN-beta-2, interleukin 6
TPGPLGGDAT SNRLPLTSAD KMEELIKYIL GKISALKKEM CDNYNKCEDS KEALAENNLN LPKLAEKDGC FQSGFNQETC LTRITTGLQE FQIYLKFLQD KYEGDKENAK SVYTSTNVLL QMLKRKGKNQ DEVTIPVPTV EVGLQAKLQS QEEWLRHTTI HLTLRRLEDF LQFSLRAVRI M (181)
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