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Equine Leukemia Inhibitory Factor (LIF) (Yeast-derived Recombinant Protein) - 500 ug (5 x 100 ug vials)

RP2117E-500
$3300.00
In Stock
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Bulk quantities of Equine LIF protein are available.
Please contact us for pricing.

Equine LIF Specifications

Molecular Weight (calculated) - 21.3kDa

Amino Acid Sequence - SPLPITPDNA TCATRHPCHS NLMDQIRNQL VQLNSSANAL FILYYTAQGE PFPSNLDKLC RPDVTDFPPF HANGKEKARL VELYRIIAYL GASLGNITRD QKVLNPNALS LHSKLNATSD TMRGLLSNVL CHLCSKYHVA NVDVAYGPDT SNKDVFQKKK LGCQLLGKYK QVIAVVAQAF QTGDLEAYSD PRS (193)

Gene ID - 100629131

Homology Across Species
Equus caballus (horse) LIF – 100%
Equus przewalskii (Przewalski's horse) LIF – 100%
Equus asinus (ass) LIF – 100%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

LIF Background

Leukemia inhibitory factor, or LIF, is a member of the IL-6 family. LIF affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. Leukemia inhibitory factor derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to LIF include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. LIF is typically added to stem cell culture medium to reduce spontaneous differentiation.

Alternate Names - LIF, CDF, DIA, HILDA, MLPLI, leukemia inhibitory factor, interleukin 6 family cytokine, LIF interleukin 6 family cytokine

Catalog No.:
RP2117E-500
Quantity:
500 ug (5 x 100 ug vials)
Source:
The Equine LIF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Equine LIF recombinant protein has a predicted molecular weight of 21.3 kDa.
Protein Sequence:

SPLPITPDNA TCATRHPCHS NLMDQIRNQL VQLNSSANAL FILYYTAQGE PFPSNLDKLC RPDVTDFPPF HANGKEKARL VELYRIIAYL GASLGNITRD QKVLNPNALS LHSKLNATSD TMRGLLSNVL CHLCSKYHVA NVDVAYGPDT SNKDVFQKKK LGCQLLGKYK QVIAVVAQAF QTGDLEAYSD PRS (193)

Alias:
LIF
Country of Origin:
USA
Applications:
The Equine LIF endotoxin-free recombinant protein can be used in cell culture, as an LIF ELISA Standard, and as a Western Blot Control.
None at this time

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USA

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