Bulk quantities of Multi-species IL-11 (Canine, Feline, Ferret, Mink) protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 19.1kDa
Amino Acid Sequence - APGPPPGPPR ASPDPRAELD SAVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LFSYLRHVQW LRRAGGPSLR TLEPELGALQ ARLDRLLRRL QLLMSRLALP QAPPDPPAPP LAPPASAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL (179)
Gene ID - 101085086 (feline)
Homology Across Species
Canis lupus familiaris (dog) IL-11 -100%
Felis catus (domestic cat) IL-11 -100%
Mustela putorius furo (domestic ferret) IL-11 -100%
Neogale vison (American mink) IL-11 -100%
Acinonyx jubatus (cheetah) IL-11 -100%
Ailuropoda melanoleuca (giant panda) IL-11 -100%
Callorhinus ursinus (northern fur seal) IL-11 -100%
Canis lupus dingo (dingo) IL-11 -100% IL-11 -100%
Gulo gulo luscus (American wolverine) IL-11 -100%
Leopardus geoffroyi (Geoffroy's cat) IL-11 -100%
Lutra lutra (Eurasian river otter) IL-11 -100%
Lynx canadensis (Canada lynx) IL-11 -100%
Lynx rufus (bobcat) IL-11 -100%
Mustela erminea (ermine) IL-11 -100%
Odobenus rosmarus divergens (Pacific walrus) IL-11 -100%
Panthera leo (lion) IL-11 -100%
Panthera pardus (leopard) IL-11 -100%
Panthera tigris (tiger) IL-11 -100%
Panthera uncia (snow leopard) IL-11 -100%
Puma concolor (puma) IL-11 -100%
Puma yagouaroundi (jaguarundi) IL-11 -100%
Vulpes vulpes (red fox) IL-11 -100%
Zalophus californianus (California sea lion) IL-11 -100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit which is expressed at high levels in fibroblasts and other stromal cells but not immune cells, unlike IL-6 receptors that are expressed at highest levels in immune cells and lowly expressed in stromal cells. IL-11 has been shown to regulate adipogenesis, osteoclastogenesis, neurogenesis and platelet maturation. Over-expression of IL-11 is associated with a variety of cancers and may provide a link between inflammation and cancer.
Alternate Names - IL11, AGIF, IL-11, interleukin 11
APGPPPGPPR ASPDPRAELD SAVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LFSYLRHVQW LRRAGGPSLR TLEPELGALQ ARLDRLLRRL QLLMSRLALP QAPPDPPAPP LAPPASAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL (179)
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