Bulk quantities of Human Defensin B1 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 3.9kDa
Amino Acid Sequence - DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK (36)
Gene ID - 1672
Homology Across Species
Homo sapiens (human) Defensin B1– 100%
Pan troglodytes (chimpanzee) Defensin B1– 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Defensins are small cysteine-rich cationic proteins across cellular life, including vertebrate and invertebrate animals, plants, and fungi. They are host defense peptides, with members displaying either direct antimicrobial activity, immune signaling activities, or both. They are variously active against bacteria, fungi and many enveloped and nonenveloped viruses. They are typically 18-45 amino acids in length, with three or four highly conserved disulfide bonds. In animals, they are produced by cells of the innate immune system and epithelial cells, whereas in plants and fungi they are produced by a wide variety of tissues. An organism usually produces many different defensins, some of which are stored inside the cells (e.g. in neutrophil granulocytes to kill phagocytosed bacteria), and others are secreted into the extracellular medium. For those that directly kill microbes, their mechanism of action varies from disruption of the microbial cell membrane to metabolic disruption.
Alternate Names - Def; GB19392; GB41428; Defensin-1
DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK (36)
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