Bulk quantities of Rat EGF protein are available.
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Molecular Weight (calculated) - 5.4kDa
Amino Acid Sequence - NSITGCPPSY DGYCLNGGVC MYVESVDRYV CNCVIGYIGE RCQHRDLR (48)
Gene ID - 25313
Homology Across Species
Rattus norvegicus (Norway rat) EGF – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
EGF (Epidermal Growth Factor) is best known for having the ability to stimulate cell growth and proliferation. There are many EGF responses and they are regulated by seven ligands: EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF-like growth factor (HBEGF), betacellulin (BTC), amphiregulin (AREG), epiregulin (EREG), and epigen (EPGN) and four ErbB (HER) family receptor tyrosine kinases: EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. EGF family members are important for development and promoting mitogenesis and differentiation of mesenchymal and epithelial cells. EGF acts as a mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. EGF plays a significant role in epithelial development, angiogenesis, regulation of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture. EGF dysregulation is also associated with the growth and progression of many cancers.
Alternate Names - EGF, HOMG4, URG, epidermal growth factor, Epidermal growth factor
NSITGCPPSY DGYCLNGGVC MYVESVDRYV CNCVIGYIGE RCQHRDLR (48)
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