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CartCynomolgus Monkey IL-1 Receptor Antagonist (IL-1RA) (Yeast-derived Recombinant Protein) - 100 micrograms
Bulk quantities of Cynomolgus Monkey IL-1RA protein are available.
Please contact us for pricing.
Cynomolgus Monkey IL-1RA Specifications
Molecular Weight (calculated) - 17.1kDa
Amino Acid Sequence - RPSGRKPSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSK NRKQDKRFAF VRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDKG VMVTKFYFQE DE (152)
Gene ID - 102126145
Homology Across Species
Macaca fascicularis (crab-eating macaque) IL-1RA – 100%
Macaca mulatta (Rhesus monkey) IL-1RA – 100%
Macaca nemestrina (pig-tailed macaque) IL-1RA – 100%
Cercocebus atys (sooty mangabey) IL-1RA – 100%
Papio anubis (olive baboon) IL-1RA – 100%
Theropithecus gelada (gelada) IL-1RA – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
IL-1RA Background
The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
Alternate Names - IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4, interleukin 1 receptor antagonist
RPSGRKPSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSK NRKQDKRFAF VRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDKG VMVTKFYFQE DE (152)
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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