Bulk quantities of Equine IL-18 protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 18.0kDa
Amino Acid Sequence - YFGRLEPKLS IIRNLNDQVL FINQGNQPVF EDMPDSDCTD NAPQTVFIIY MYKDSLTRGL AVTISVKCEK TSTLSCKNKI ISFKEMSPPE NINDEGNDII FFQRSVPGHD DKIQFESSLY KGYFLACEKE NDLFKLILKE KDENGDKSVM FTVQNQN (157)
Homology Across Species
Equus caballus (horse) IL-18 – 100%
Equus przewalskii (Przewalski's horse) IL-18 – 100%
Equus asinus (ass) IL-18 – 100%
Equus quagga (plains zebra) IL-18 – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
The interleukin-1 superfamily has 11 members, which have similar gene structure. Interleukin 18 (IL-18), also know an IL-1F4, was isolated as a co-factor that, in synergism with IL-12, stimulated the production of IFN gamma in Th1 cells. It is now understood that IL-18 is an important link between innate and adaptive immune responses and a regulator of both cellular and humoral immunity. IL-18 is secreted in its active form following cleavage by caspase 1 in response to inflammatory and infectious stimuli. In addition to its effects on Th1 cells, IL-18 is a strong stimulator of the activity of natural killer cells alone or in combination with IL-15, and of CD8+ lymphocytes. Together with IL-2, IL-18 can also stimulate the production of IL-13 and of other Th2 cytokines. IL-18 plays a role in numerous inflammatory-associated disorders.
Alternate Names - IL18, IGIF, IL-18, IL-1g, IL1F4, interleukin 18
YFGRLEPKLS IIRNLNDQVL FINQGNQPVF EDMPDSDCTD NAPQTVFIIY MYKDSLTRGL AVTISVKCEK TSTLSCKNKI ISFKEMSPPE NINDEGNDII FFQRSVPGHD DKIQFESSLY KGYFLACEKE NDLFKLILKE KDENGDKSVM FTVQNQN (157)
Please note that Cookies and JavaScript are required for you to view this website.
Check if you have Cookies and JavaScript enabled in your browser