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Equine IL-18 (Yeast-derived Recombinant Protein) - 500 micrograms

RP2218E-500
$3300.00
In Stock
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Bulk quantities of Equine IL-18 protein are available.
Please contact us for pricing.

Equine IL-18 Specifications

Molecular Weight (calculated) - 18.0kDa

Amino Acid Sequence - YFGRLEPKLS IIRNLNDQVL FINQGNQPVF EDMPDSDCTD NAPQTVFIIY MYKDSLTRGL AVTISVKCEK TSTLSCKNKI ISFKEMSPPE NINDEGNDII FFQRSVPGHD DKIQFESSLY KGYFLACEKE NDLFKLILKE KDENGDKSVM FTVQNQN (157)

Homology Across Species
Equus caballus (horse) IL-18 – 100%
Equus przewalskii (Przewalski's horse) IL-18 – 100%
Equus asinus (ass) IL-18 – 100%
Equus quagga (plains zebra) IL-18 – 100%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

IL-18 Background

The interleukin-1 superfamily has 11 members, which have similar gene structure. Interleukin 18 (IL-18), also know an IL-1F4, was isolated as a co-factor that, in synergism with IL-12, stimulated the production of IFN gamma in Th1 cells. It is now understood that IL-18 is an important link between innate and adaptive immune responses and a regulator of both cellular and humoral immunity. IL-18 is secreted in its active form following cleavage by caspase 1 in response to inflammatory and infectious stimuli. In addition to its effects on Th1 cells, IL-18 is a strong stimulator of the activity of natural killer cells alone or in combination with IL-15, and of CD8+ lymphocytes. Together with IL-2, IL-18 can also stimulate the production of IL-13 and of other Th2 cytokines. IL-18 plays a role in numerous inflammatory-associated disorders.

Alternate Names - IL18, IGIF, IL-18, IL-1g, IL1F4, interleukin 18

Catalog No.:
RP2218E-500
Quantity:
500 ug
Source:
The Equine IL-18 recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Equine IL-18 recombinant protein has a predicted molecular weight of 18.0 kDa.
Protein Sequence:

YFGRLEPKLS IIRNLNDQVL FINQGNQPVF EDMPDSDCTD NAPQTVFIIY MYKDSLTRGL AVTISVKCEK TSTLSCKNKI ISFKEMSPPE NINDEGNDII FFQRSVPGHD DKIQFESSLY KGYFLACEKE NDLFKLILKE KDENGDKSVM FTVQNQN (157)

Alias:
IL-1F4
Country of Origin:
USA
Applications:
The Equine IL-18 endotoxin-free recombinant protein can be used in cell culture, as an IL-18 ELISA Standard, and as a Western Blot Control.
None at this time

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USA

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