Bulk quantities of Human CCL17 protein are available.
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Molecular Weight (calculated) - 8.08kDa
Amino Acid Sequence - ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S (71)
Homology Across Species
Homo sapiens (human) CCL17 – 100%
Gorilla gorilla gorilla (western lowland gorilla) CCL17 – 100%
Pan troglodytes (chimpanzee) CCL17 – 100%
Pan paniscus (pygmy chimpanzee) CCL17 – 99%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
CCL17 (CC chemokine ligand 17) was initially named TARC (thymus- and activation-regulated chemokine). CCL17 as well as its partner chemokine CCL22 induce chemotaxis in T-helper cells. It is one of the few chemokines that are not stored in the body, except in the thymus; these chemokines are made when needed by dendritic cells, macrophages, and monocytes. CCL17 is expressed constitutively in the thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It can also be detected in other tissues such as the colon, small intestine, and lung. Granulocyte-macrophage colony-stimulating factor (GM-CSF) upregulates CCL17 production in monocytes and macrophages. Dendritic cells will produce large quantities of CCL17 when stimulated with IL-4 or TSLP.
Alternate Names - CCL17, A-152E5.3, ABCD-2, SCYA17, TARC, C-C motif chemokine ligand 17
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S (71)
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