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CartCanine IL-12 p70 (Yeast-derived Recombinant Protein) - 5 micrograms
Bulk quantities of Canine IL-12 p70 protein are available.
Please contact us for pricing.
Canine IL-12 p70 Specifications
Molecular Weight (calculated) - 57.9kDa
Amino Acid Sequence - IWELEKDVYV VELDWHPDAP GEMVVLTCHT PEEDDITWTS AQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGKVLSRSLL LIHKKEDGIW STDILKEQKE SKNKIFLKCE AKNYSGRFTC WWLTAISTDL KFSVKSSRGF SDPQGVTCGA VTLSAERVRV DNRDYKKYTV ECQEGSACPS AEESLPIEVV VDAIHKLKYE NYTSSFFIRD IIKPDPPTNL QLKPLKNSRH VEVSWEYPDT WSTPHSYFSL TFCVQAQGKN NREKKDRLCV DKTSAKVVCH KDAKIRVQAR DRYYSSSWSD WASVSCS (307) **LINKER** RSLPTASPSP GIFQCLNHSQ NLLRAVSNTL QKARQTLDYI PCTSEEIDHE DITKDKTSTV EACLPLELTM NESCLASREI SLITNGSCLA SGKASFMTVL CLSSIYEDLK MYQMEFKAMN AKLLMDPKRQ IFLDQNMLTA IDELLQALNF NSVTVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRM MSYLNSS (197)
Homology Across Species
Canis lupus familiaris (dog) IL-12p70 - 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
IL-12 p70 Background
IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-gamma and TNF-alpha from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-gamma.
Alternate Names - IL-12A, CLMF1, NKSF1, p35; IL-12B, CLMF2, NKSF2, p40
IWELEKDVYV VELDWHPDAP GEMVVLTCHT PEEDDITWTS AQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGKVLSRSLL LIHKKEDGIW STDILKEQKE SKNKIFLKCE AKNYSGRFTC WWLTAISTDL KFSVKSSRGF SDPQGVTCGA VTLSAERVRV DNRDYKKYTV ECQEGSACPS AEESLPIEVV VDAIHKLKYE NYTSSFFIRD IIKPDPPTNL QLKPLKNSRH VEVSWEYPDT WSTPHSYFSL TFCVQAQGKN NREKKDRLCV DKTSAKVVCH KDAKIRVQAR DRYYSSSWSD WASVSCS (307) **LINKER** RSLPTASPSP GIFQCLNHSQ NLLRAVSNTL QKARQTLDYI PCTSEEIDHE DITKDKTSTV EACLPLELTM NESCLASREI SLITNGSCLA SGKASFMTVL CLSSIYEDLK MYQMEFKAMN AKLLMDPKRQ IFLDQNMLTA IDELLQALNF NSVTVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRM MSYLNSS (197)
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Kingfisher Biotech, Inc.
1000 Westgate Drive
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Saint Paul, MN 55114
USA
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