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CartEquine IL-1 beta Polyclonal Antibody - Biotinylated
Reactivity - ELISA
Bovine IL-1β - None
Canine IL-1β - None
Dolphin IL-1β - None
Equine IL-1β - Strong
Feline IL-1β - None
Guinea Pig IL-1β - None
Human IL-1β - None
Mouse IL-1β - None
Ovine IL-1β - None
Rabbit IL-1β - None
Swine IL-1β - None
Turkey IL-1β - None
Equine IL-1β ELISA Data
Effects of Orally Administered Resveratrol on TNF, IL-1β, Leukocyte Phagocytic Activity and Oxidative Burst Function in Horses: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study.
Martin LM, Johnson PJ, Amorim JR, DeClue AE.
Int J Mol Sci. 2020 Feb 20;21(4). pii: E1453. doi: 10.3390/ijms21041453.
Applications: Measurement of equine IL-1 beta in cell culture supernatant by ELISA
Abstract
Resveratrol, a phytophenol, is a commonly used equine nutraceutical supplement touted to exert anti-inflammatory effects. The effect of orally administered resveratrol on tumor necrosis factor (TNF), interleukin-1β (IL-1β), leukocyte phagocytic activity or oxidative burst function have not been reported in horses. The objective of this study was to determine the effects of a commercially available, orally administered resveratrol product on innate immune functions in healthy adult horses. Whole blood was collected from 12 horses prior to and following 3 weeks of treatment with either the manufacturer's recommended dose of resveratrol or placebo. Phagocytosis, oxidative burst and pathogen associated molecular pattern (PAMP) motif-stimulated leukocyte production of TNF and IL-1β were compared pre- and post-treatment between treatment groups. Phagocytosis and oxidative burst capacity were evaluated via flow cytometry. Tumor necrosis factor and IL-1β were measured using cytotoxicity and ELISA assays, respectively. There were no significant differences in phagocytosis, oxidative burst or stimulated TNF or IL-1β production between resveratrol and placebo treatment groups. Orally administered resveratrol at a routinely recommended dose for a duration of 3 weeks did not significantly affect phagocytic activity, oxidative burst function or PAMP-stimulated leukocyte cytokine production.
Feeding Grass Hay Before Concentrate Mitigates the Effect of Grain-Based Concentrates on Postprandial Plasma Interleukin-1β.
Suagee-Bedore JK, Linden DR, Bennett-Wimbush K, Splan RK.
J Equine Vet Sci. 2020 Mar;86:102899. doi: 10.1016/j.jevs.2019.102899. Epub 2019 Dec 24.
Applications: Measurement of equine IL-1 beta in plasma by ELISA
Increasing platelet concentrations in leukocyte-reduced platelet-rich plasma decrease collagen gene synthesis in tendons.
Boswell SG, Schnabel LV, Mohammed HO, Sundman EA, Minas T, Fortier LA.
Am J Sports Med. 2014 Jan;42(1):42-9. doi: 10.1177/0363546513507566. Epub 2013 Oct 17.
Applications: Measurement of equine IL-1 beta in platelet-rich plasma by ELISA
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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA
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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.
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